Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.33 |
| ▸ | F3 | P13726 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835801 | 0.87 | LMNA (0.34) | LMNAALDH1A1FAAHEPHX2HSD17B10 | |
| SCHEMBL9835164 | 0.80 | FAAH (0.39) | LMNAFAAHEPHX2HSD17B10CYP3A4 | |
| SCHEMBL9836015 | 0.75 | ALOX5 (0.45) | EPHX2TDP1MAPTKMT2AMEN1 | |
| SCHEMBL9836441 | 0.74 | EPHX2 (0.40) | LMNAFAAHEPHX2HSD17B10CYP3A4 | |
| SCHEMBL9836289 | 0.73 | EPHX2 (0.41) | LMNAFAAHEPHX2HSD17B10CYP3A4 | |
| SCHEMBL6168566 | 0.72 | ALDH1A1 (0.60) | LMNAALDH1A1FAAHHSD17B10CYP3A4 | |
| SCHEMBL6166639 | 0.72 | ALDH1A1 (0.60) | LMNAALDH1A1FAAHHSD17B10CYP3A4 | |
| SCHEMBL6168911 | 0.71 | LMNA (0.66) | LMNAALDH1A1EPHX2HSD17B10CYP3A4 | |
| SCHEMBL6167108 | 0.71 | LMNA (0.66) | LMNAALDH1A1EPHX2HSD17B10CYP3A4 | |
| SCHEMBL9835526 | 0.70 | BCHE (0.44) | LMNAALDH1A1FAAHEPHX2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |