Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.45 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836140 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAALMNAPOLB | |
| SCHEMBL6859087 | 0.82 | MAOA (0.60) | ALDH1A1KDM4EGAALMNAPOLB | |
| SCHEMBL9836869 | 0.81 | LMNA (0.59) | ALDH1A1KDM4EGAALMNAPOLB | |
| SCHEMBL9834498 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAALMNAPOLB | |
| SCHEMBL9836652 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAALMNAPOLB | |
| SCHEMBL9834762 | 0.78 | LMNA (0.57) | ALDH1A1KDM4EGAALMNAPOLB | |
| SCHEMBL9837083 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAALMNAPOLB | |
| SCHEMBL9836782 | 0.77 | KMT2A (0.57) | ALDH1A1KDM4EGAALMNAPOLB | |
| SCHEMBL9836000 | 0.77 | NPC1 (0.53) | ALDH1A1KDM4EGAALMNAPOLB | |
| SCHEMBL14473803 | 0.76 | KCNA3 (0.63) | ALDH1A1KDM4EGAALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0175376-A2 | Xanthone derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-03-26 | — | — | EP | disclosed |