Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837306 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL22699151 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7910336 | 0.77 | SLC9A1 (0.48) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7910316 | 0.77 | SLC9A1 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8132478 | 0.76 | SLC9A1 (0.62) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7910295 | 0.74 | SLC9A1 (0.65) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| Maleic Acid SCHEMBL29406656 | 0.74 | SLC9A1 (0.86) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| Maleic Acid SCHEMBL7916788 | 0.72 | SLC9A1 (0.54) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL22699251 | 0.72 | SMN1; SMN2 (0.42) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8260539 | 0.70 | RAB9A (0.48) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210782-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |
| US-4778796-A | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0210782-A2 | Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-02-04 | — | — | EP | disclosed |