Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682063 | 0.78 | NPC1 (0.41) | SLC9A1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9837302 | 0.77 | ALDH1A1 (0.56) | SLC9A1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9837306 | 0.77 | ALDH1A1 (0.56) | SLC9A1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL8260539 | 0.75 | RAB9A (0.48) | SLC9A1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9681811 | 0.75 | NPC1 (0.44) | SMN1; SMN2ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL22699151 | 0.74 | ALDH1A1 (0.48) | SLC9A1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL7910295 | 0.72 | SLC9A1 (0.65) | SLC9A1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL12507659 | 0.71 | SMN1; SMN2 (0.48) | SLC9A1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL11729324 | 0.71 | SMN1; SMN2 (0.48) | SLC9A1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL10314494 | 0.71 | KDM4E (0.46) | SLC9A1SMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |