Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918967 | 0.87 | HPGD (0.45) | KIF11KMT2AMAOBMAPTPOLB | |
| SCHEMBL9837994 | 0.80 | MAPT (0.36) | KIF11KMT2AMEN1ACHEMAPT | |
| SCHEMBL1315596 | 0.79 | MAPK1 (0.44) | KIF11KMT2AMEN1MAPT | |
| SCHEMBL30913780 | 0.76 | MAPK1 (0.42) | KIF11KMT2AMEN1MAOBMAPT | |
| SCHEMBL6170678 | 0.76 | TSHR (0.41) | MAPTPOLBLMNA | |
| SCHEMBL9837406 | 0.75 | ALDH1A1 (0.37) | MAOB | |
| SCHEMBL6172247 | 0.75 | PRKCA (0.38) | KMT2AMEN1MAPT | |
| SCHEMBL6170855 | 0.75 | UNG (0.40) | KMT2AMEN1MAOBMAPTCES1 | |
| SCHEMBL9836483 | 0.74 | PTPN5 (0.36) | KIF11KMT2AMEN1LMNA | |
| SCHEMBL309330 | 0.72 | ACHE (0.65) | KIF11KMT2AMEN1ACHEKCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219308-B1 | 2-SUBSTITUTED QUINOLINES | MERCK FROSST CANADA INC. (CA) | 1991-10-23 | — | — | EP | disclosed |