Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837406 | 0.81 | ALDH1A1 (0.37) | UNGALDH1A1TRIM24TRIM33ALOX15 | |
| SCHEMBL6170678 | 0.81 | TSHR (0.41) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL7451104 | 0.80 | UNG (0.36) | UNGALDH1A1TRIM24TRIM33TP53 | |
| SCHEMBL6172247 | 0.80 | PRKCA (0.38) | RXRARXRBTP53MAPTSMN1; SMN2 | |
| SCHEMBL9837387 | 0.75 | KIF11 (0.45) | MAPTMAOBMEN1KMT2ACES1 | |
| SCHEMBL1315596 | 0.74 | MAPK1 (0.44) | ALDH1A1ALOX15CYP3A4MAPTMAPK1 | |
| SCHEMBL10544293 | 0.73 | SMN1; SMN2 (0.50) | UNGALDH1A1TRIM24TRIM33ALOX15 | |
| SCHEMBL5918967 | 0.73 | HPGD (0.45) | ALDH1A1MAPTSMN1; SMN2TDP1MAOB | |
| SCHEMBL1587498 | 0.72 | ALDH1A1 (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL2997840 | 0.70 | CES2 (0.48) | UNGALDH1A1TRIM24TRIM33RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192127-B1 | SUBSTITUTED BENZAMIDE INHIBITORS OF RHINOVIRUS 3C PROTEASE | AGOURON PHARMA (US) | 2005-03-30 | — | — | EP | disclosed |