Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835733 | 0.84 | ALOX5 (0.52) | ALOX5TAS1R3TAS1R1 | |
| SCHEMBL9629268 | 0.71 | ALOX5 (0.77) | ALOX5NPC1 | |
| SCHEMBL19974181 | 0.67 | PKM (0.39) | GAAALDH1A1LMNAMAPT | |
| SCHEMBL27826011 | 0.66 | ALOX5 (0.33) | ALOX5ALDH1A1TAS1R3TAS1R1NPC1 | |
| SCHEMBL27795453 | 0.66 | FAAH (0.57) | GAA | |
| SCHEMBL28707004 | 0.65 | ALDH1A1 (0.40) | GAAALDH1A1LMNAMAPT | |
| SCHEMBL20495881 | 0.64 | KDM4E (0.34) | GAAALDH1A1 | |
| SCHEMBL27853400 | 0.64 | SMN1; SMN2 (0.34) | GAAALDH1A1LMNAMAPT | |
| SCHEMBL9205678 | 0.64 | ALDH1A1 (0.52) | ALDH1A1NPC1MAPT | |
| SCHEMBL27572170 | 0.64 | SSTR4 (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457803-A4 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | — | 1991-12-04 | — | — | EP | disclosed |