Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837435 | 0.84 | ALOX5 (0.38) | ALOX5TAS1R3TAS1R1 | |
| SCHEMBL9628650 | 0.69 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL13647150 | 0.67 | ALDH1A1 (0.55) | — | |
| SCHEMBL14206511 | 0.66 | PARP10 (0.37) | — | |
| SCHEMBL6194776 | 0.66 | FBP1 (0.36) | — | |
| SCHEMBL11708039 | 0.66 | BRD4 (0.41) | — | |
| SCHEMBL23810063 | 0.64 | KDM4E (0.35) | — | |
| SCHEMBL28772041 | 0.64 | L3MBTL1 (0.42) | — | |
| SCHEMBL680649 | 0.63 | — | — | |
| SCHEMBL9327664 | 0.62 | PLK1 (0.65) | PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457803-A4 | 4-HYDROXYTHIAZOLES AS 5-LIPOXYGENASE INHIBITORS | — | 1991-12-04 | — | — | EP | disclosed |