Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839459 | 0.92 | LTA4H (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8845637 | 0.91 | OPRM1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9839254 | 0.90 | OPRM1 (0.46) | MAOBMAOARAB9AMAPTNPC1 | |
| SCHEMBL9838108 | 0.84 | LTA4H (0.43) | RAB9AMAPTNPC1TP53KMT2A | |
| SCHEMBL9838128 | 0.83 | BCHE (0.46) | MAOBRAB9ANPC1TP53PTGS2 | |
| SCHEMBL9839431 | 0.80 | BCHE (0.46) | MAOBRAB9ANPC1TP53PTGS2 | |
| SCHEMBL9839168 | 0.77 | LTA4H (0.49) | RAB9AMAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL9839855 | 0.71 | MAOB (0.41) | MAOBMAOAKDM1ASMN1; SMN2MEN1 | |
| SCHEMBL8845424 | 0.71 | CA1 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8845428 | 0.71 | CA1 (0.50) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |