Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845637 | 0.98 | OPRM1 (0.44) | OPRM1OPRL1CA4MAPTLTA4H | |
| SCHEMBL9838108 | 0.91 | LTA4H (0.43) | OPRM1OPRL1CA4MAPTLTA4H | |
| SCHEMBL9837820 | 0.90 | CA12 (0.42) | OPRM1OPRL1MAPTHSD11B1ALDH1A1 | |
| SCHEMBL9839431 | 0.86 | BCHE (0.46) | MAOBNPC1RAB9AKMT2A | |
| SCHEMBL9839855 | 0.86 | MAOB (0.41) | ALDH1A1MAOBMAOAKMT2A | |
| SCHEMBL9838128 | 0.83 | BCHE (0.46) | MAOBNPC1RAB9AKMT2A | |
| SCHEMBL9839168 | 0.83 | LTA4H (0.49) | OPRM1MAPTLTA4HNPC1RAB9A | |
| SCHEMBL9839459 | 0.82 | LTA4H (0.47) | MAPTLTA4HMAPK1MAOBMAOA | |
| SCHEMBL9839248 | 0.79 | AKR1B1 (0.37) | CA4MAPTLTA4HALDH1A1MAOB | |
| SCHEMBL10575136 | 0.79 | AKR1B1 (0.37) | CA4MAPTLTA4HALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |