Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839431 | 0.97 | BCHE (0.46) | BCHEMEN1KMT2AMAOBTP53 | |
| SCHEMBL8845637 | 0.84 | OPRM1 (0.44) | KMT2AMAOBTP53RAB9ASMN1; SMN2 | |
| SCHEMBL9839254 | 0.83 | OPRM1 (0.46) | KMT2AMAOBRAB9ANPC1 | |
| SCHEMBL9837820 | 0.83 | CA12 (0.42) | MEN1KMT2AMAOBTP53RAB9A | |
| SCHEMBL8913782 | 0.81 | MAOB (0.50) | BCHEMEN1KMT2AMAOBTP53 | |
| SCHEMBL8913779 | 0.81 | MAOB (0.50) | BCHEMEN1KMT2AMAOBTP53 | |
| SCHEMBL9838108 | 0.81 | LTA4H (0.43) | KMT2ATP53RAB9APKMAPP | |
| SCHEMBL8913796 | 0.81 | MAOB (0.50) | BCHEMEN1KMT2AMAOBTP53 | |
| SCHEMBL9839459 | 0.79 | LTA4H (0.47) | KMT2AMAOBTP53RAB9ASMN1; SMN2 | |
| SCHEMBL9839168 | 0.79 | LTA4H (0.49) | MEN1KMT2ATP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |