Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.41 |
| ▸ | KDM5C | P41229 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM6B | O15054 | 3/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL17975779 | 0.78 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL25307640 | 0.77 | CES1 (0.41) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL409946 | 0.76 | EGLN1 (0.53) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL2305765 | 0.74 | EGLN1 (0.69) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL9839268 | 0.73 | LMNA (0.46) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL7702279 | 0.73 | EGLN1 (0.56) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL21776012 | 0.72 | LMNA (0.47) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL10369361 | 0.72 | EGLN1 (0.47) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL18630261 | 0.72 | EGLN1 (0.47) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL35204 | 0.71 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004734-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 4,6-TIOXOHEPTANOIC ACID OR ITS DERIVATIVES | CETUS CORPORATION (US) | 1991-04-18 | — | — | WO | disclosed |
| WO-1990000049-A2 | IMMUNOSUPPRESSIVE ANALOGUES AND DERIVATIVES OF SUCCINYLACETONE | CETUS CORPORATION (US) | 1990-01-11 | — | — | WO | disclosed |