SCHEMBL9838804

SCHEMBL9838804

N#Cc1ccc2c(c1)OOC2(F)F

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 1/20 0.34
ABCB1 P08183 7/20 0.33
PDK2 Q15119 1/20 0.33
CYP2A6 P11509 1/20 0.33
PTGS2 P35354 1/20 0.32
KDM1A O60341 2/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
DRD2 P14416 2/20 0.32
DRD3 P35462 2/20 0.32
PNMT P11086 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL623724 0.72 TDP2 (0.39) P2RY6ABCB1CYP2A6PTGS2CA12
SCHEMBL5139262 0.72 TDP2 (0.44) ABCB1CYP2A6PTGS2CA12CA9
SCHEMBL14043141 0.69 KDM4E (0.39) ABCB1
SCHEMBL31085054 0.66 DAO (0.36) ABCB1CYP2A6CA12CA9DRD2
SCHEMBL11619301 0.63 CA12 (0.47) CYP2A6CA12CA9
SCHEMBL31287181 0.62 ABCC9 (0.36) ABCB1PDK2
SCHEMBL11022031 0.62 PNMT (0.43) CYP2A6KDM1ACA12CA9DRD2
SCHEMBL31362085 0.62 SNCA (0.42) CYP2A6CA12CA9DRD2DRD3
SCHEMBL28398312 0.62 SNCA (0.42) CYP2A6CA12CA9DRD2DRD3
SCHEMBL29618319 0.60 PNMT (0.46) PDK2KDM1ADRD2DRD3PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424125-A2 Aralkylamine derivatives, preparation method thereof and fungicides containing the same UBE INDUSTRIES, LTD. (JP) 1991-04-24 EP disclosed