Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366901 | 0.73 | TSHR (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL5633862 | 0.69 | LMNA (0.73) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL7523445 | 0.68 | NR1H2 (0.41) | NR1H2LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL583468 | 0.67 | NR1H2 (0.55) | NR1H2LMNAHIF1AMEN1ESR1 | |
| SCHEMBL2977565 | 0.66 | ESR1 (0.70) | ABATENPP2ESR1FNTAFNTB | |
| SCHEMBL2904570 | 0.65 | LMNA (0.66) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL4070672 | 0.64 | LMNA (0.77) | NR1H2LMNACYP1A2SLC6A2CYP2C19 | |
| SCHEMBL537145 | 0.64 | LMNA (0.45) | NR1H2LMNAHDAC6KDM4EALDH1A1 | |
| SCHEMBL27458843 | 0.64 | LMNA (0.63) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL2303871 | 0.63 | NR1H2 (0.50) | NR1H2LMNASLC6A2SLC6A3HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5024699-A | Colorfast images; absorption in near-infrared | RICOH COMPANY, LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| US-4981970-A | LEUCO DYES, RECORDING | RICOH COMPANY, LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
| US-4940691-A | Coloring phthalide compounds and recording materials using the compounds as coloring component | RICOH COMPANY, LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| US-4925828-A | STABILITY; INFRARED ABSORBANCE | RICOH COMPANY, LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4880762-A | OPTICAL RECORDING MEDIA | RICOH COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |