Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
| ▸ | ASPH | Q12797 | 1/20 | 0.30 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365445 | 0.68 | KEAP1 (0.35) | TOP2ATOP2BBBOX1ASPHKDM8 | |
| SCHEMBL5546400 | 0.67 | ALDH1A1 (0.38) | KDM4EALDH1A1TOP2ALMNAHPGD | |
| SCHEMBL3816673 | 0.67 | KCNH2 (0.34) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9184531 | 0.65 | KDM4E (0.72) | KDM4EALDH1A1TOP2ALMNAHPGD | |
| SCHEMBL9717143 | 0.65 | DRD3 (0.47) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL17775397 | 0.64 | TOP2A (0.42) | KMT2AKDM4EALDH1A1TOP2ALMNA | |
| SCHEMBL8802209 | 0.63 | TOP1 (0.31) | — | |
| SCHEMBL16329562 | 0.63 | TOP2A (0.55) | KDM4EALDH1A1TOP2ALMNAHPGD | |
| SCHEMBL22015414 | 0.62 | TOP2A (0.44) | MEN1KMT2AKDM4EALDH1A1TOP2A | |
| SCHEMBL8775559 | 0.61 | TOP2A (0.35) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002526-A1 | AZABICYCLO QUINOLONE CARBOXYLIC ACIDS | PFIZER INC. (US) | 1991-03-07 | — | — | WO | disclosed |