SCHEMBL984086

SCHEMBL984086

CC(C)c1ccccc1Oc1ccccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.59
GABRB2 P47870 2/20 0.59
P2RX3 P56373 1/20 0.49
P2RX2 Q9UBL9 1/20 0.49
TSHR P16473 3/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
TP53 P04637 2/20 0.48
LMNA P02545 4/20 0.45
SLC6A2 P23975 3/20 0.45
CYP3A4 P08684 2/20 0.45
HPGD P15428 2/20 0.45
FAAH O00519 1/20 0.45
CYP1A2 P05177 1/20 0.45
GABRB1 P18505 1/20 0.45
GABRG2 P18507 1/20 0.45
PTGS1 P23219 1/20 0.45
HTR2C P28335 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRA5 P31644 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29959656 0.87 P2RX3 (0.58) GABRA1GABRB2P2RX3P2RX2TSHR
SCHEMBL4575432 0.87 P2RX3 (0.58) GABRA1GABRB2P2RX3P2RX2TSHR
SCHEMBL4920377 0.83 GABRA1 (0.48) GABRA1GABRB2P2RX3P2RX2TSHR
SCHEMBL5168243 0.83 LMNA (0.49) GABRA1GABRB2TSHRCA1CA2
SCHEMBL984038 0.82 TSHR (0.67) GABRA1GABRB2TSHRCA1CA2
SCHEMBL18197 0.80 CA2 (0.62) TSHRCA1CA2TP53LMNA
SCHEMBL29446988 0.80 CA2 (0.62) TSHRCA1CA2TP53LMNA
SCHEMBL982177 0.79 TSHR (0.48) GABRA1GABRB2TSHRCA1CA2
SCHEMBL984129 0.79 TSHR (0.49) GABRA1GABRB2TSHRCA1CA2
Methoxymethane SCHEMBL7185958 0.78 CA2 (0.68) TSHRCA1CA2TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003002081-A1 COMPOSITION COMPRISING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002078-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002080-A1 COMPOSITIONS CONTAINING A DERIVATIVE OF HYDROXYDIPHENYL ETHER INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002072-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'ORÉAL (FR) 2003-01-09 WO claimed
WO-2003002079-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
EP-2275405-B1 PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE ASAHI CHEMICAL IND (JP) 2019-04-24 EP disclosed
EP-2275406-B1 PROCESS FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2018-11-28 EP disclosed
EP-2792673-B1 Carbamic acid ester derivatives for the production of isocyanate and aromatic hydroxy compounds ASAHI CHEMICAL IND (JP) 2018-07-25 EP disclosed
US-9637445-B2 Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-05-02 US disclosed
EP-2147909-B1 METHOD FOR PRODUCTION OF ISOCYANATE USING COMPOSITION COMPRISING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSPORT OR STORAGE OF CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2016-12-14 EP disclosed
US-9233918-B2 Isocyanate production process ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-01-12 US disclosed
US-20150259279-A1 Isocyanate Production Process Using Composition Containing Carbamic Acid Ester and Aromatic Hydroxy Compound, and Composition for Transfer and Storage of Carbamic Acid Ester ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-09-17 US disclosed
EP-1494640-A1 USE OF HYDROXYDIPHENYL ETHER DERIVATIVES AS ARYLSULFATASE- INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS Ciba SC Holding AG (CH) 2005-01-12 EP disclosed
WO-2004050079-A1 COMPOSITION COMPRISING A CARBAMIC ACID DERIVATIVE, ITS USE AS COSMETIC AND MEDICINE LABORATOIRES EXPANSCIENCE (FR) 2004-06-17 WO disclosed
WO-2003086338-A1 USE OF HYDROXYDIPHENYL ETHER DERIVATIVES AS ARYLSULFATASE- INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-10-23 WO disclosed
WO-2003002080-A1 COMPOSITIONS CONTAINING A DERIVATIVE OF HYDROXYDIPHENYL ETHER INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO disclosed
WO-2003002081-A1 COMPOSITION COMPRISING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO disclosed
WO-2003002078-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO disclosed
WO-2003002072-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'ORÉAL (FR) 2003-01-09 WO disclosed
WO-2003002079-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259279-A1 Isocyanate Production Process Using Composition Containing Carbamic Acid Ester and Aromatic Hydroxy Compound, and Composition for Transfer and Storage of Carbamic Acid Ester PAH, APEH, CPS1 GABRA1 2484/4885GABRB2 2619/4885P2RX3 3597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.