Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010571 | 0.84 | LMNA (0.48) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL7546534 | 0.83 | CA1 (0.48) | LMNATRPA1CA1CA2TP53 | |
| SCHEMBL984086 | 0.83 | GABRA1 (0.59) | LMNASLC6A2HTR2BGABRA1GABRB2 | |
| SCHEMBL465786 | 0.75 | HTR2A (0.47) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL7545091 | 0.75 | TRPA1 (0.48) | TRPA1GABRA1GABRB2CA1CA2 | |
| SCHEMBL6186016 | 0.74 | ALDH1A1 (0.48) | LMNACA1CA2TP53TSHR | |
| SCHEMBL6436713 | 0.73 | SLC6A4 (0.45) | LMNASLC6A2TSHRHTR2ASLC6A4 | |
| SCHEMBL6284868 | 0.73 | LMNA (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL24998819 | 0.73 | LPAR1 (0.37) | LMNASLC6A2MEN1KMT2ATSHR | |
| SCHEMBL981248 | 0.73 | TSHR (0.54) | LMNATRPA1MEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773125-A1 | 5-IODOTETRAZOLES | Lanxess Deutschland GmbH (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006012996-A1 | 5-IODOTETRAZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |