Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691541 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL8998172 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL17736530 | 0.92 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL25228385 | 0.86 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL3482402 | 0.84 | LMNA (0.42) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL8465959 | 0.84 | DGKA (0.43) | ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL8463255 | 0.84 | DGKA (0.43) | ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL8463526 | 0.84 | DGKA (0.43) | ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL16295140 | 0.84 | DGKA (0.43) | ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL134075 | 0.82 | TSHR (0.43) | ALDH1A1LMNAMAPTTSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061762-A | MODIFIED POLY(ORGANO-ORGANOSILOXANES) WITH COMB OR BLOCK STRUCTURES AND A PROCESS FOR THEIR PREPARATION | WACKER-CHEMIE GMBH (DE) | 1991-10-29 | — | — | US | disclosed |