SCHEMBL3482402

SCHEMBL3482402

C=CCCC(=O)O[Si](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.42
FAAH O00519 4/20 0.36
MGLL Q99685 2/20 0.36
MAPT P10636 2/20 0.34
ABCC4 O15439 1/20 0.34
TSHR P16473 1/20 0.32
USP2 O75604 1/20 0.31
CYP3A4 P08684 1/20 0.31
RECQL P46063 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17736530 0.88 ALDH1A1 (0.53) LMNAALDH1A1FAAHMGLLMAPT
SCHEMBL9840921 0.84 ALDH1A1 (0.65) LMNAALDH1A1MAPTABCC4TSHR
SCHEMBL1691541 0.84 ALDH1A1 (0.65) LMNAALDH1A1MAPTABCC4TSHR
SCHEMBL8998172 0.84 ALDH1A1 (0.65) LMNAALDH1A1MAPTABCC4TSHR
SCHEMBL7195048 0.80 LMNA (0.38) LMNAALDH1A1FAAHMGLLMAPT
SCHEMBL4303758 0.78 TSHR (0.45) LMNAALDH1A1MAPTTSHR
SCHEMBL5586614 0.77 HTT (0.34) LMNAALDH1A1TSHR
SCHEMBL29187275 0.76 ALDH1A1 (0.38) LMNAALDH1A1FAAHMGLLMAPT
SCHEMBL4641466 0.75 TSHR (0.32) TSHR
SCHEMBL514725 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1641063-B1 POLYMER ELECTROLYTE, POLYMER ELECTROLYTE MEMBRANE THEREFROM, MEMBRANE ELECTRODE ASSEMBLY AND POLYMER ELECTROLYTE FUEL CELL TORAY INDUSTRIES (JP) 2018-06-20 EP disclosed
US-8455141-B2 Polymer electrolyte as well as polymer electrolyte membrane, membrane electrode assembly and polymer electrolyte fuel cell using the same TORAY INDUSTRIES, INC. (JP) 2013-06-04 US disclosed
US-8420764-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8420764-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8420764-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8236917-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2012-08-07 US disclosed
US-8236917-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2012-08-07 US disclosed
US-8236917-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2012-08-07 US disclosed
US-20120178894-A1 COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER INAGAKI JYUN-ICHI (JP) 2012-07-12 US disclosed
US-20120178894-A1 COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER INAGAKI JYUN-ICHI (JP) 2012-07-12 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed
US-20070134530-A1 Polymer electrolyte as well as polymer electrolyte membrane, membrane electrode assembly and polymer electrolyte fuel cell using the same TORAY INDUSTRIES, INC. (JP) 2007-06-14 US disclosed
CN-1788377-A Polymer electrolyte, polymer electrolyte membrane therefrom, membrane electrode assembly and polymer electrolyte fuel cell TORAY INDUSTRIES (JP) 2006-06-14 CN disclosed
US-7053167-B2 Silsesquioxane derivative having functional group CHISSO CORPORATION (JP) 2006-05-30 US disclosed
US-20060089504-A1 Silsesquioxane derivative having functional group ITO KENYA 2006-04-27 US disclosed
EP-1641063-A1 POLYMER ELECTROLYTE, POLYMER ELECTROLYTE MEMBRANE THEREFROM, MEMBRANE ELECTRODE ASSEMBLY AND POLYMER ELECTROLYTE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-03-29 EP disclosed
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance CHISSO CORPORATION (JP) 2006-03-09 US disclosed
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer CHISSO CORPORATION (JP) 2005-01-13 US disclosed
US-20040068074-A1 Production process for silsesquioxane derivative having functional group and silsesquioxane derivative JNC CORPORATION (JP) 2004-04-08 US disclosed
US-5061762-A MODIFIED POLY(ORGANO-ORGANOSILOXANES) WITH COMB OR BLOCK STRUCTURES AND A PROCESS FOR THEIR PREPARATION WACKER-CHEMIE GMBH (DE) 1991-10-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance STS, PFAS, POLQ LMNA 2213/4885ALDH1A1 2132/4885FAAH 545/4885
US-20060089504-A1 Silsesquioxane derivative having functional group SFXN1, STS, SRM LMNA 2228/4885ALDH1A1 597/4885FAAH 4260/4885
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer C1S, H1-4, H1-0 LMNA 280/4885ALDH1A1 1780/4885FAAH 4471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.