Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | GRM8 | O00222 | 3/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | GRM6 | O15303 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MYOC | Q99972 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL9840960 | 1.00 | KMT2A (0.51) | KMT2AALOX15BLMPMP22GRM8 | |
| SCHEMBL7275811 | 0.82 | BCL9 (0.50) | KMT2AMAPTBCL9CTNNB1ALDH1A1 | |
| SCHEMBL9840744 | 0.82 | BCL9 (0.50) | KMT2AMAPTBCL9CTNNB1ALDH1A1 | |
| SCHEMBL4227635 | 0.79 | ALDH1A1 (0.53) | KMT2AGRM8GRM4GRM6MAPT | |
| SCHEMBL27723656 | 0.79 | ALDH1A1 (0.53) | KMT2AGRM8GRM4GRM6MAPT | |
| Glutamic Acid SCHEMBL3126271 | 0.76 | GRM8 (0.53) | KMT2AGRM8GRM4GRM6MEN1 | |
| SCHEMBL8350753 | 0.76 | RAB9A (0.52) | RAB9AALDH1A1 | |
| Glutamine SCHEMBL1487701 | 0.76 | KMT2A (0.76) | KMT2AALOX15BLMPMP22GRM8 | |
| Glutamine SCHEMBL1487702 | 0.76 | KMT2A (0.76) | KMT2AALOX15BLMPMP22GRM8 | |
| Glutamine SCHEMBL2517416 | 0.76 | KMT2A (0.76) | KMT2AALOX15BLMPMP22GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990614-A | N-heterocyclic amides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |