Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GRM8 | O00222 | 2/20 | 0.54 |
| ▸ | GRM6 | O15303 | 2/20 | 0.54 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL1487702 | 1.00 | KMT2A (0.76) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL2517415 | 1.00 | KMT2A (0.76) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL2517416 | 1.00 | KMT2A (0.76) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL2514139 | 1.00 | KMT2A (0.76) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL2514140 | 1.00 | KMT2A (0.76) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL411575 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL711605 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL411170 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL994966 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR | |
| Glutamine SCHEMBL7453 | 0.87 | KMT2A (1.00) | KMT2AALOX15BLMPMP22GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448357-B1 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2025-10-21 | — | — | US | claimed |
| US-12240819-B1 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2025-03-04 | — | — | US | claimed |
| US-11155524-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2021-10-26 | — | — | US | claimed |
| US-20200297678-A1 | Amino Acid Compositions | THERMOLIFE INTERNATIONAL, LLC | 2020-09-24 | — | — | US | claimed |
| US-20260115150-A1 | FORMULATIONS COMPRISING INOSITOL, SILICATES, AND OPTIONALLY AMINO ACIDS WITH IMPROVED SOLUBILITY AND METHODS OF MAKING THE SAME | NUTRITION21 LLC (US) | 2026-04-30 | — | — | US | disclosed |
| US-12612370-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-04-28 | — | — | US | disclosed |
| US-12577209-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-03-17 | — | — | US | disclosed |
| US-12577210-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-03-17 | — | — | US | disclosed |
| US-12540119-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-02-03 | — | — | US | disclosed |
| US-12522568-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-01-13 | — | — | US | disclosed |
| US-12473261-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2025-11-18 | — | — | US | disclosed |
| US-12448357-B1 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2025-10-21 | — | — | US | disclosed |
| US-20110064720-A1 | Dietary Supplement Compositions and Methods of Making and Using the Same | AMATO DANIEL MOSES | 2011-03-17 | — | — | US | disclosed |
| US-20110064712-A1 | Dietary Supplement Compositions and Methods of Making and Using the Same | AMATO DANIEL MOSES | 2011-03-17 | — | — | US | disclosed |
| CN-101817762-A | Preparation method of L-glutamine nitrate | TIANJIN TIANCHENG PHARMACEUTICAL CO LTD | 2010-09-01 | — | — | CN | disclosed |
| CN-101817762-A | Preparation method of L-glutamine nitrate | TIANJIN TIANCHENG PHARMACEUTICAL CO LTD | 2010-09-01 | — | — | CN | disclosed |
| CN-101817762-A | Preparation method of L-glutamine nitrate | TIANJIN TIANCHENG PHARMACEUTICAL CO LTD | 2010-09-01 | — | — | CN | disclosed |
| US-7777074-B2 | Amino acid compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2010-08-17 | — | — | US | disclosed |
| US-20090105328-A1 | Amino Acid Compounds | THERMOLIFE INTERNATIONAL, LLC | 2009-04-23 | — | — | US | disclosed |
| US-20090076110-A1 | Amino Acid Compounds | THERMOLIFE INTERNATIONAL, LLC | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473261-B2 | Amino acid compositions | ASNS, GLUL, ARGLU1 | KMT2A 1875/4885ALOX15 2572/4885BLM 4752/4885 |
| US-12612370-B2 | Amino acid compositions | TNNT2, NPR1, NOS2 | KMT2A 3285/4885ALOX15 2601/4885BLM 4815/4885 |
| US-12448357-B1 | Amino acid compositions | SLC6A15, SLC1A5, SLC6A19 | KMT2A 3664/4885ALOX15 2510/4885BLM 4587/4885 |
| US-12540119-B2 | Amino acid compositions | NOS2, NOS1, NOS3 | KMT2A 1532/4885ALOX15 4000/4885BLM 4810/4885 |
| US-20090076110-A1 | Amino Acid Compounds | OAT, ARGLU1, ASNS | KMT2A 1863/4885ALOX15 3711/4885BLM 3808/4885 |
| US-20110064720-A1 | Dietary Supplement Compositions and Methods of Making and Using the Same | SLC5A6, PNLIP, LIPC | KMT2A 3008/4885ALOX15 100/4885BLM 1477/4885 |
| US-12240819-B1 | Amino acid compositions | SLC10A2, SLC1A5, CPT1B | KMT2A 3774/4885ALOX15 1321/4885BLM 3372/4885 |
| US-12577209-B2 | Amino acid compositions | ARG1, NOS1, NOS2 | KMT2A 3153/4885ALOX15 3027/4885BLM 4747/4885 |
| US-20090105328-A1 | Amino Acid Compounds | DNPEP, AADAT, ASNS | KMT2A 1801/4885ALOX15 2667/4885BLM 4840/4885 |
| US-12577210-B2 | Amino acid compositions | NPR1, SLC1A5, SLC6A15 | KMT2A 2504/4885ALOX15 3144/4885BLM 4863/4885 |
| US-20110064712-A1 | Dietary Supplement Compositions and Methods of Making and Using the Same | SLC5A6, PNLIP, LIPC | KMT2A 3008/4885ALOX15 100/4885BLM 1477/4885 |
| US-20200297678-A1 | Amino Acid Compositions | ASNS, ARGLU1, SLC6A15 | KMT2A 1850/4885ALOX15 4265/4885BLM 4105/4885 |
| US-20260115150-A1 | FORMULATIONS COMPRISING INOSITOL, SILICATES, AND OPTIONALLY AMINO ACIDS WITH IMPROVED SOLUBILITY AND METHODS OF MAKING THE SAME | CUTA, NOS1, NOS2 | KMT2A 1129/4885ALOX15 3512/4885BLM 3655/4885 |
| US-11155524-B2 | Amino acid compositions | ASNS, ARGLU1, SLC6A15 | KMT2A 1850/4885ALOX15 4265/4885BLM 4105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.