Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18850851 | 0.79 | MARK3 (0.36) | — | |
| SCHEMBL9840977 | 0.78 | HTR2A (0.34) | — | |
| SCHEMBL9505759 | 0.71 | LMNA (0.35) | MPITDP1 | |
| SCHEMBL4602685 | 0.67 | TDP1 (0.45) | MPITDP1 | |
| SCHEMBL5464264 | 0.62 | MPI (0.56) | MPITDP1 | |
| SCHEMBL4603835 | 0.62 | KMT2A (0.53) | MPITDP1 | |
| SCHEMBL918366 | 0.62 | HTT (0.51) | MPITDP1RAB9A | |
| SCHEMBL8397425 | 0.62 | HTT (0.51) | MPITDP1RAB9A | |
| SCHEMBL9840924 | 0.61 | MPI (0.37) | MPITDP1 | |
| SCHEMBL4602213 | 0.61 | TDP1 (0.43) | MPITDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4986934-A | SPIROBENZOXAZINE PYRROLOPYRIDINE COMPOUNDS, EYEGLASSES | PPG INDUSTRIES, INC. (US) | 1991-01-22 | — | — | US | disclosed |