Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842022 | 0.89 | SIGMAR1 (0.41) | KMT2ACA1CA2CA4CA9 | |
| SCHEMBL9842205 | 0.77 | OPRD1 (0.43) | KMT2AOPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9842280 | 0.76 | MITF (0.47) | MITFTAAR1TDP1HTR2AIDE | |
| SCHEMBL9842333 | 0.75 | ALDH1A1 (0.50) | KDM4EKMT2AL3MBTL1 | |
| SCHEMBL6619234 | 0.74 | MITF (0.52) | MITFTAAR1TDP1IDEUBE2N | |
| SCHEMBL9842315 | 0.73 | OPRD1 (0.41) | KDM4EKMT2AOPRD1SLC6A2SLC6A4 | |
| SCHEMBL4892854 | 0.73 | GRM2 (0.50) | MITFKCNH2KMT2AHTR2AOPRD1 | |
| SCHEMBL31541868 | 0.72 | SLC6A2 (0.43) | MITFTAAR1KCNH2KMT2ACA1 | |
| SCHEMBL16846249 | 0.72 | SIGMAR1 (0.50) | MITFTAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27802994 | 0.71 | MITF (0.49) | MITFTAAR1TDP1IDEUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461264-A1 | ETHYNYLPHENYL DERIVATIVE, PRODUCTION THEREOF, AND REMEDY FOR DISEASES OF CIRCULATORY ORGANS CONTAINING THE SAME AS ACTIVE INGREDIENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |