Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842205 | 0.93 | OPRD1 (0.43) | OPRD1OPRM1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL9842323 | 0.90 | OPRD1 (0.35) | OPRD1OPRM1OPRK1SLC6A9KMT2A | |
| SCHEMBL9841934 | 0.84 | OPRD1 (0.42) | OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL9842117 | 0.83 | OPRD1 (0.36) | OPRD1OPRM1SLC6A9KMT2A | |
| SCHEMBL9842320 | 0.77 | OPRD1 (0.36) | OPRD1OPRM1OPRK1KMT2A | |
| SCHEMBL9842022 | 0.75 | SIGMAR1 (0.41) | SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL9842276 | 0.73 | MITF (0.47) | OPRD1SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL8051571 | 0.73 | MEN1 (0.47) | OPRD1OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9842330 | 0.72 | OPRD1 (0.42) | OPRD1OPRM1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL9842111 | 0.72 | OPRD1 (0.40) | OPRD1OPRM1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461264-A1 | ETHYNYLPHENYL DERIVATIVE, PRODUCTION THEREOF, AND REMEDY FOR DISEASES OF CIRCULATORY ORGANS CONTAINING THE SAME AS ACTIVE INGREDIENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |