Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842210 | 0.80 | OPRD1 (0.38) | OPRD1OPRM1MEN1KMT2ASLC6A9 | |
| SCHEMBL9842337 | 0.76 | OPRD1 (0.39) | OPRD1OPRM1MEN1KMT2ASLC6A9 | |
| SCHEMBL27402701 | 0.74 | MEN1 (0.51) | OPRD1OPRM1MEN1KMT2A | |
| SCHEMBL9842320 | 0.74 | OPRD1 (0.36) | OPRD1OPRM1KMT2AOPRK1 | |
| SCHEMBL4449286 | 0.73 | OPRD1 (0.42) | OPRD1OPRM1MEN1KMT2ASLC6A9 | |
| SCHEMBL9842206 | 0.72 | OPRD1 (0.40) | OPRD1OPRM1MEN1KMT2ASLC6A9 | |
| SCHEMBL9842205 | 0.72 | OPRD1 (0.43) | OPRD1OPRM1MEN1KMT2ASLC6A9 | |
| SCHEMBL8051571 | 0.72 | MEN1 (0.47) | OPRD1OPRM1MEN1KMT2A | |
| SCHEMBL4275538 | 0.71 | MEN1 (0.44) | OPRD1OPRM1MEN1KMT2AOPRK1 | |
| SCHEMBL9842111 | 0.71 | OPRD1 (0.40) | OPRD1OPRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461264-A1 | ETHYNYLPHENYL DERIVATIVE, PRODUCTION THEREOF, AND REMEDY FOR DISEASES OF CIRCULATORY ORGANS CONTAINING THE SAME AS ACTIVE INGREDIENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |