Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842206 | 0.87 | OPRD1 (0.40) | OPRD1SLC6A9OPRM1MEN1KMT2A | |
| SCHEMBL9842021 | 0.80 | TDP1 (0.42) | TDP1KMT2A | |
| SCHEMBL9842330 | 0.78 | OPRD1 (0.42) | OPRD1OPRM1TDP1MEN1KMT2A | |
| SCHEMBL9842210 | 0.78 | OPRD1 (0.38) | OPRD1SLC6A9OPRM1MEN1KMT2A | |
| SCHEMBL9842287 | 0.76 | OPRD1 (0.39) | OPRD1SLC6A9OPRM1MEN1KMT2A | |
| SCHEMBL3919530 | 0.74 | MEN1 (0.50) | OPRD1OPRM1MEN1KMT2AOPRK1 | |
| SCHEMBL9842293 | 0.73 | OPRD1 (0.39) | OPRD1OPRM1MEN1KMT2ACHRM2 | |
| SCHEMBL9842320 | 0.72 | OPRD1 (0.36) | OPRD1OPRM1KMT2AOPRK1 | |
| SCHEMBL7317029 | 0.70 | MEN1 (0.51) | OPRD1OPRM1MEN1KMT2AOPRK1 | |
| SCHEMBL9842200 | 0.70 | OPRD1 (0.42) | OPRD1OPRM1MEN1KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461264-A1 | ETHYNYLPHENYL DERIVATIVE, PRODUCTION THEREOF, AND REMEDY FOR DISEASES OF CIRCULATORY ORGANS CONTAINING THE SAME AS ACTIVE INGREDIENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |