Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749669 | 0.72 | ESR1 (0.43) | BRD4CREBBPCNR2TTRESR1 | |
| SCHEMBL3459068 | 0.61 | ENTPD5 (0.47) | BRD4CREBBPMRGPRX2PTPN1MAPT | |
| SCHEMBL7250459 | 0.60 | OPRM1 (0.37) | BRD4CREBBPTTRESR1ESR2 | |
| SCHEMBL7248834 | 0.60 | OPRM1 (0.37) | BRD4CREBBPTTRESR1ESR2 | |
| SCHEMBL282032 | 0.60 | ALDH1A1 (0.60) | CNR2TTRESR1ESR2OPRM1 | |
| SCHEMBL5547664 | 0.60 | BRD4 (0.55) | BRD4CREBBPTTRESR1ESR2 | |
| SCHEMBL11649138 | 0.60 | OPRM1 (0.60) | MRGPRX2OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL5051071 | 0.59 | OPRM1 (0.46) | ESR1ESR2MRGPRX2OPRM1OPRD1 | |
| SCHEMBL19194418 | 0.58 | ESR1 (0.61) | BRD4CREBBPCNR2TTRESR1 | |
| SCHEMBL31254037 | 0.58 | ALDH1A1 (0.49) | ESR1ESR2OPRM1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411433-A2 | Branched polycarbonate and process for production thereof | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |