Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459068 | 0.87 | ENTPD5 (0.47) | MRGPRX2BRD4CREBBPMAPTHIF1A | |
| SCHEMBL27479840 | 0.80 | HIF1A (0.38) | KDM4EALDH1A1CYP3A4MAPTHSD17B10 | |
| SCHEMBL10382447 | 0.75 | SMN1; SMN2 (0.36) | BRD4CREBBPKDM4EMAPK1 | |
| SCHEMBL9842553 | 0.72 | BRD4 (0.33) | ESR1ESR2TTRCNR2MRGPRX2 | |
| SCHEMBL7250459 | 0.72 | OPRM1 (0.37) | ESR1ESR2TTRBRD4CREBBP | |
| SCHEMBL7248834 | 0.72 | OPRM1 (0.37) | ESR1ESR2TTRBRD4CREBBP | |
| SCHEMBL28339856 | 0.72 | ALOX15 (0.40) | CNR2KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL5547664 | 0.72 | BRD4 (0.55) | ESR1ESR2TTRBRD4CREBBP | |
| SCHEMBL282032 | 0.72 | ALDH1A1 (0.60) | ESR1ESR2TTRCNR2OPRM1 | |
| SCHEMBL11649138 | 0.72 | OPRM1 (0.60) | MRGPRX2OPRM1OPRD1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230475-B1 | NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |