Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.60 |
| ▸ | ABL1 | P00519 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427050 | 0.83 | TRPV1 (0.56) | TRPV1HTTSMN1; SMN2EPHX2NPC1 | |
| SCHEMBL9843014 | 0.82 | NPC1 (0.60) | TRPV1HTTSMN1; SMN2EPHX2NPC1 | |
| SCHEMBL9843089 | 0.82 | RAB9A (0.64) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9842892 | 0.80 | HDAC6 (0.44) | TRPV1ABL1OPRM1KCNH2 | |
| SCHEMBL8597230 | 0.80 | NPC1 (0.56) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2914329 | 0.79 | TRPV1 (0.74) | TRPV1ABL1MEN1KMT2AHTT | |
| SCHEMBL9842954 | 0.78 | NQO2 (0.54) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL29458444 | 0.78 | TRPV1 (0.63) | TRPV1ABL1MEN1KMT2AHTT | |
| SCHEMBL11435148 | 0.77 | TRPV1 (0.56) | TRPV1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6709253 | 0.77 | KIF11 (0.50) | TRPV1ABL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | claimed |
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |