Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526172 | 0.83 | MAOA (0.47) | MAOAMAOBPTGES2CYP3A4TSHR | |
| SCHEMBL10701243 | 0.78 | MAOA (0.42) | MAOAMAOBALDH1A1MAPT | |
| SCHEMBL9436499 | 0.77 | MAOA (0.39) | MAOAMAOBPTGES2CYP3A4MEN1 | |
| SCHEMBL9498520 | 0.75 | SMN1; SMN2 (0.48) | TSHRALDH1A1MMP2CA9 | |
| SCHEMBL2866425 | 0.74 | MAOA (0.45) | MAOAMAOBPTGES2CYP3A4TSHR | |
| SCHEMBL15413487 | 0.72 | MAOA (0.44) | MAOAMAOBCA12CA9CA14 | |
| SCHEMBL9488126 | 0.72 | MAOA (0.44) | MAOAMAOBPTGES2CYP3A4TSHR | |
| SCHEMBL9645780 | 0.71 | CES2 (0.41) | MAOAMAOB | |
| SCHEMBL9488123 | 0.71 | MAOA (0.42) | MAOAMAOBPTGES2CYP3A4MEN1 | |
| SCHEMBL9494682 | 0.71 | HSD11B1 (0.52) | MEN1ALDH1A1KMT2ACA12MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435794-A1 | Alkenyl- or heteroaryl thio, sulfone, sulfoxy herbicides | RHONE-POULENC AGROCHIMIE (FR) | 1991-07-03 | — | — | EP | disclosed |