Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843775 | 0.85 | MAOB (0.44) | LOXL2MAOB | |
| SCHEMBL6299352 | 0.83 | GABRA1 (0.47) | LOXL2MAOBGABRA1GABRB2 | |
| SCHEMBL21455346 | 0.83 | LOXL2 (0.44) | LOXL2MAOB | |
| SCHEMBL20765731 | 0.79 | PSMB5 (0.42) | — | |
| SCHEMBL17652301 | 0.79 | PSMB5 (0.42) | — | |
| SCHEMBL13298379 | 0.79 | CYP17A1 (0.40) | MAOB | |
| SCHEMBL31534803 | 0.79 | LOXL2 (0.32) | LOXL2MAOB | |
| SCHEMBL7962995 | 0.75 | ALDH1A1 (0.49) | — | |
| SCHEMBL5544888 | 0.75 | LOXL2 (0.33) | LOXL2MAOB | |
| SCHEMBL3281151 | 0.74 | MAOB (0.53) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025055856-A1 | P53-Y220C-SELECTIVE SMALL-MOLECULE REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 长春金赛药业有限责任公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-118852259-A | P53-Y220C selective small molecule reactivation agent compound, pharmaceutical composition and application thereof | 长春金赛药业有限责任公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117986235-A | P53-Y220C selective small molecule reactivation agent compound, pharmaceutical composition and application thereof | 长春金赛药业有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| EP-0445073-A1 | Benzofurans | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |