Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679094 | 0.90 | HTR1A (0.46) | HTR1AKCNH2HTR2ADRD2KMT2A | |
| SCHEMBL9844433 | 0.86 | SIGMAR1 (0.45) | KCNH2HTR2AKMT2A | |
| SCHEMBL9844329 | 0.85 | SIGMAR1 (0.54) | HTR1AKCNH2HTR2AKMT2A | |
| SCHEMBL9844499 | 0.84 | HTR2A (0.53) | KCNH2HTR2AKMT2A | |
| SCHEMBL9844336 | 0.83 | GRM2 (0.56) | HTR7KCNH2HTR2A | |
| SCHEMBL9844082 | 0.83 | SLC6A2 (0.60) | HTR7KMT2ACYP2C19 | |
| SCHEMBL9844242 | 0.82 | HTR2A (0.52) | HTR7HTR2ACYP2D6 | |
| SCHEMBL9844227 | 0.80 | SIGMAR1 (0.59) | HTR7HTR1ATMEM97 | |
| SCHEMBL9844055 | 0.80 | GRM2 (0.49) | HTR7HTR1AKCNH2HTR2AKMT2A | |
| SCHEMBL9844308 | 0.79 | MAOA (0.56) | KCNH2HTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |