Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.61 |
| ▸ | DRD2 | P14416 | 4/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.61 |
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.61 |
| ▸ | HRH1 | P35367 | 3/20 | 0.61 |
| ▸ | HTR2B | P41595 | 3/20 | 0.61 |
| ▸ | HTR6 | P50406 | 3/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844492 | 0.94 | OPRM1 (0.56) | OPRM1OPRK1CYP1A2CYP2D6DRD2 | |
| SCHEMBL9844225 | 0.91 | PLD2 (0.56) | OPRM1OPRK1CYP1A2CYP2D6DRD2 | |
| SCHEMBL9844310 | 0.89 | OPRM1 (0.57) | OPRM1OPRK1CYP1A2CYP2D6DRD2 | |
| SCHEMBL9844276 | 0.86 | GRM2 (0.51) | OPRM1OPRK1CYP1A2CYP2D6DRD2 | |
| SCHEMBL9844116 | 0.85 | PLD2 (0.53) | OPRM1OPRK1CYP1A2CYP2D6DRD2 | |
| SCHEMBL9844431 | 0.85 | OPRM1 (0.53) | OPRM1OPRK1CYP1A2CYP2D6DRD2 | |
| SCHEMBL9677855 | 0.85 | OPRM1 (0.67) | OPRM1OPRK1CYP1A2CYP2D6DRD2 | |
| SCHEMBL9844265 | 0.84 | OPRM1 (0.58) | OPRM1OPRK1CYP1A2CYP2D6DRD2 | |
| SCHEMBL9844300 | 0.84 | OPRM1 (0.52) | OPRM1OPRK1CYP1A2CYP2D6DRD2 | |
| SCHEMBL9455222 | 0.81 | OPRM1 (0.68) | OPRM1OPRK1CYP1A2CYP2D6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |