Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD2 | O14939 | 2/20 | 0.56 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844492 | 0.94 | OPRM1 (0.56) | OPRL1OPRM1OPRK1OPRD1MEN1 | |
| SCHEMBL9844394 | 0.91 | OPRM1 (0.61) | PLD2PLD1OPRL1OPRM1OPRK1 | |
| SCHEMBL9844310 | 0.89 | OPRM1 (0.57) | OPRL1OPRM1OPRK1MEN1CYP1A2 | |
| SCHEMBL9844276 | 0.86 | GRM2 (0.51) | PLD2PLD1OPRL1OPRM1OPRK1 | |
| SCHEMBL9844431 | 0.85 | OPRM1 (0.53) | PLD2PLD1OPRL1OPRM1OPRK1 | |
| SCHEMBL9677855 | 0.85 | OPRM1 (0.67) | OPRL1OPRM1OPRK1OPRD1MEN1 | |
| SCHEMBL9844265 | 0.84 | OPRM1 (0.58) | PLD2PLD1OPRL1OPRM1OPRK1 | |
| SCHEMBL9844116 | 0.84 | PLD2 (0.53) | PLD2OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL9844300 | 0.82 | OPRM1 (0.52) | PLD2PLD1OPRL1OPRM1OPRK1 | |
| SCHEMBL9844231 | 0.79 | SIGMAR1 (0.63) | OPRL1OPRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |