Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.58 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.51 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844310 | 0.92 | OPRM1 (0.57) | OPRM1OPRL1HTR1AGRM2OPRK1 | |
| SCHEMBL9844431 | 0.90 | OPRM1 (0.53) | OPRM1OPRL1HTR1AOPRK1DRD2 | |
| SCHEMBL9844276 | 0.90 | GRM2 (0.51) | OPRM1OPRL1HTR1AGRM2OPRK1 | |
| SCHEMBL9844492 | 0.89 | OPRM1 (0.56) | OPRM1OPRL1HTR1AOPRK1DRD2 | |
| SCHEMBL9844300 | 0.86 | OPRM1 (0.52) | OPRM1OPRL1HTR1AOPRK1DRD2 | |
| SCHEMBL9844116 | 0.86 | PLD2 (0.53) | OPRM1OPRL1HTR1AGRM2OPRK1 | |
| SCHEMBL9844225 | 0.84 | PLD2 (0.56) | OPRM1OPRL1HTR1AOPRK1DRD2 | |
| SCHEMBL9844394 | 0.84 | OPRM1 (0.61) | OPRM1OPRL1HTR1AOPRK1DRD2 | |
| SCHEMBL9844085 | 0.81 | SIGMAR1 (0.68) | GRM2SIGMAR1HTR7 | |
| SCHEMBL10388553 | 0.81 | HTR1A (0.55) | OPRM1OPRL1HTR1AOPRK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |