Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.54 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844265 | 0.92 | OPRM1 (0.58) | OPRM1OPRL1SIGMAR1HTR1AGRM2 | |
| SCHEMBL9844492 | 0.92 | OPRM1 (0.56) | OPRM1OPRL1SIGMAR1HTR1ASLC6A9 | |
| SCHEMBL9844431 | 0.89 | OPRM1 (0.53) | OPRM1OPRL1SIGMAR1HTR1ASLC6A9 | |
| SCHEMBL9844225 | 0.89 | PLD2 (0.56) | OPRM1OPRL1HTR1ASLC6A9SLC6A5 | |
| SCHEMBL9844394 | 0.89 | OPRM1 (0.61) | OPRM1OPRL1SIGMAR1HTR1ASLC6A9 | |
| SCHEMBL9844300 | 0.87 | OPRM1 (0.52) | OPRM1OPRL1SIGMAR1HTR1ASLC6A9 | |
| SCHEMBL9844276 | 0.85 | GRM2 (0.51) | OPRM1OPRL1HTR1AGRM2SLC6A9 | |
| SCHEMBL9677855 | 0.82 | OPRM1 (0.67) | OPRM1OPRL1SIGMAR1HTR1ASLC6A9 | |
| SCHEMBL9844116 | 0.81 | PLD2 (0.53) | OPRM1OPRL1SIGMAR1HTR1AGRM2 | |
| SCHEMBL10388553 | 0.80 | HTR1A (0.55) | OPRM1OPRL1SIGMAR1HTR1ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |