Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483409 | 0.85 | RAB9A (0.48) | L3MBTL1CYP1A2CYP3A4CYP2C9HTT | |
| SCHEMBL7578887 | 0.84 | LMNA (0.50) | L3MBTL1CYP1A2CYP3A4CYP2C9HTT | |
| Hydrochloric Acid SCHEMBL1695958 | 0.84 | RAB9A (0.47) | L3MBTL1CYP1A2CYP3A4CYP2C9HTT | |
| SCHEMBL7574624 | 0.82 | ALDH1A1 (0.42) | L3MBTL1CYP1A2CYP3A4CYP2C9HTT | |
| SCHEMBL2485161 | 0.79 | MEN1 (0.45) | L3MBTL1RPS6KB1AURKACYP3A4CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL17997772 | 0.78 | MEN1 (0.44) | L3MBTL1RPS6KB1AURKACYP3A4CYP2D6 | |
| SCHEMBL9844488 | 0.76 | ALDH1A1 (0.42) | L3MBTL1HTTHPGDNPC1RAB9A | |
| SCHEMBL7574770 | 0.76 | ALDH1A1 (0.61) | CYP1A2CYP3A4CYP2C9HTTCYP2C19 | |
| SCHEMBL7584780 | 0.75 | KMT2A (0.46) | L3MBTL1HTTNPC1RAB9ALMNA | |
| SCHEMBL7583940 | 0.74 | BRD4 (0.57) | HTTRAB9ALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |