Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735956 | 0.72 | NOTUM (0.62) | NOTUMLMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL3825385 | 0.68 | NQO1 (0.68) | CA12CA1CYP1A2CA4CA6 | |
| SCHEMBL29629327 | 0.68 | NQO1 (0.68) | CA12CA1CYP1A2CA4CA6 | |
| SCHEMBL21335672 | 0.65 | MAPT (0.46) | LMNACA12CA1CYP1A2CA4 | |
| SCHEMBL21335573 | 0.65 | ALDH1A1 (0.48) | LMNACA12CA1CYP1A2CA4 | |
| SCHEMBL6073833 | 0.65 | CYP11B2 (0.52) | LMNACYP1A2MAPT | |
| SCHEMBL23458226 | 0.64 | NQO1 (0.62) | CA12CA1CYP1A2CA4CA6 | |
| SCHEMBL3821099 | 0.64 | NQO1 (0.62) | CA12CA1CYP1A2CA4CA6 | |
| SCHEMBL29779700 | 0.64 | NQO1 (0.62) | CA12CA1CYP1A2CA4CA6 | |
| SCHEMBL28405864 | 0.64 | MAPT (0.42) | LMNACA12CA1CYP1A2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441517-A2 | Tricyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1991-08-14 | — | — | EP | disclosed |