Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258755 | 0.89 | CCR3 (0.56) | CCR3SIGMAR1ACHE | |
| SCHEMBL2004615 | 0.73 | CCR3 (1.00) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL7977320 | 0.72 | CCR3 (0.96) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL8191786 | 0.72 | CCR3 (0.96) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL4508006 | 0.71 | ACHE (0.52) | ALDH1A1KMT2AACHESMN1; SMN2 | |
| SCHEMBL9264946 | 0.71 | ACHE (0.48) | KDM4ESIGMAR1ACHEDRD4 | |
| SCHEMBL4508009 | 0.71 | ACHE (0.52) | ALDH1A1KMT2AACHESMN1; SMN2 | |
| SCHEMBL16208334 | 0.69 | SIGMAR1 (0.67) | CCR3SIGMAR1 | |
| SCHEMBL9844722 | 0.69 | ACHE (0.46) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL8251054 | 0.69 | CCR3 (0.81) | CCR3ALDH1A1ATMGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441517-A2 | Tricyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1991-08-14 | — | — | EP | disclosed |