Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 9/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844783 | 0.73 | EP300 (0.39) | EP300CYP4A11CYP4F2TLR8MAPT | |
| SCHEMBL8997153 | 0.70 | CYP4A11 (0.36) | EP300CYP4A11CYP4F2MEN1KMT2A | |
| SCHEMBL9844822 | 0.69 | TBXAS1 (0.37) | EP300MEN1KMT2AHRH1MAPT | |
| SCHEMBL8997195 | 0.64 | ATIC (0.35) | EP300CYP4A11CYP4F2MEN1KMT2A | |
| SCHEMBL8997209 | 0.64 | CYP4A11 (0.43) | EP300CYP4A11CYP4F2TLR8 | |
| SCHEMBL10169575 | 0.62 | CYP4A11 (0.68) | CYP4A11CYP4F2MEN1KMT2ALMNA | |
| SCHEMBL12176878 | 0.61 | CYP4A11 (0.70) | CYP4A11CYP4F2LMNAMAPT | |
| SCHEMBL19922842 | 0.61 | CYP4A11 (0.60) | CYP4A11CYP4F2MEN1KMT2AHRH1 | |
| SCHEMBL7505320 | 0.61 | CYP4A11 (0.60) | CYP4A11CYP4F2HRH1MAPTTHRB | |
| SCHEMBL19609284 | 0.60 | CYP4A11 (0.56) | CYP4A11CYP4F2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |