Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 10/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844790 | 0.73 | EP300 (0.38) | EP300CYP4A11CYP4F2TLR8MAPT | |
| SCHEMBL9844770 | 0.68 | EP300 (0.49) | EP300CYP4A11CYP4F2CYP1A2CYP3A4 | |
| SCHEMBL9844748 | 0.67 | DRD2 (0.39) | EP300MAPTTHRB | |
| SCHEMBL9844768 | 0.67 | TBXAS1 (0.39) | EP300MAPT | |
| SCHEMBL12176878 | 0.65 | CYP4A11 (0.70) | CYP4A11CYP4F2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8982456 | 0.62 | CYP4A11 (0.48) | EP300CYP4A11CYP4F2CYP1A2CYP3A4 | |
| SCHEMBL10169575 | 0.61 | CYP4A11 (0.68) | CYP4A11CYP4F2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5733406 | 0.61 | CYP4A11 (0.72) | CYP4A11CYP4F2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13230897 | 0.61 | CYP4A11 (0.72) | CYP4A11CYP4F2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8982447 | 0.61 | CYP4A11 (0.48) | EP300CYP4A11CYP4F2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |