SCHEMBL9844867

SCHEMBL9844867

Cc1cc(S(=O)(=O)Cl)c(C)c(C)c1OCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.41
ACLY P53396 1/20 0.41
CD69 Q07108 2/20 0.40
ELANE P08246 1/20 0.40
KMT2A Q03164 1/20 0.39
PTGDR2 Q9Y5Y4 2/20 0.38
KDM4E B2RXH2 2/20 0.38
PKM P14618 1/20 0.37
HTT P42858 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
HPGD P15428 1/20 0.37
PTPRB P23467 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15969206 0.77 PPARG (0.46) PTGDR2POLBTSHR
SCHEMBL9844869 0.76 HTT (0.41) ELANEKMT2AKDM4EPKMHTT
SCHEMBL1038076 0.75 ALDH1A1 (0.57) KMT2APKMHTTPOLBTSHR
SCHEMBL7285425 0.74 PTGDR2 (0.43) MCL1PTGDR2TSHR
SCHEMBL20906749 0.72 MCL1 (0.40) MCL1ACLYCD69ELANEKMT2A
SCHEMBL11570516 0.72 KDM4E (0.55) MCL1KMT2APTGDR2KDM4EPKM
SCHEMBL2059355 0.71 CSNK2A2 (0.49) MCL1CD69ELANEKMT2APTGDR2
SCHEMBL5367871 0.70 MCL1 (0.55) MCL1KMT2AKDM4EPOLBGAA
SCHEMBL6744370 0.70 SMN1; SMN2 (0.51) MCL1ACLYCD69KMT2AHTT
SCHEMBL2058911 0.70 THRA (0.47) MCL1CD69ELANEKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413839-A1 GHRH analogs The Administrators of The Tulane Educational Fund (US) 1991-02-27 EP disclosed
US-4914189-A STIMULATES RELEASE OF GROWTH HORMONE THE ADMINSTRATORS OF THE TULANE EDUCATIONAL FUND (US) 1990-04-03 US disclosed