Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 10/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592322 | 0.78 | CYP19A1 (0.42) | LMNACYP3A4 | |
| Acetic Acid SCHEMBL27871968 | 0.73 | LMNA (0.42) | KCNA5LMNA | |
| SCHEMBL11240104 | 0.72 | CYP3A4 (0.42) | LMNACYP3A4 | |
| SCHEMBL22904827 | 0.71 | CYP24A1 (0.35) | CYP3A4 | |
| SCHEMBL2369398 | 0.69 | ALDH1A1 (0.50) | LMNACYP1A2CYP3A4TDP1 | |
| SCHEMBL9494010 | 0.69 | KCNA5 (0.49) | KCNA5KCNH2LMNACYP1A2CYP3A4 | |
| SCHEMBL12238648 | 0.69 | CYP3A4 (0.49) | KCNA5KCNH2LMNACYP1A2CYP3A4 | |
| SCHEMBL1055295 | 0.68 | CYP3A4 (0.39) | LMNACYP3A4 | |
| SCHEMBL18326357 | 0.68 | CYP19A1 (0.45) | KCNA5LMNACYP3A4 | |
| SCHEMBL3021832 | 0.68 | CYP19A1 (0.55) | KCNA5LMNACYP1A2CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435127-A2 | 3-Substituted pyridines | BASF Aktiengesellschaft (DE) | 1991-07-03 | — | — | EP | disclosed |