Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LIG1 | P18858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16200702 | 0.75 | PLAU (0.48) | PLAUPKMLIG1 | |
| SCHEMBL6057113 | 0.67 | — | — | |
| SCHEMBL26245693 | 0.63 | PLAU (0.38) | PLAUPKMLIG1 | |
| SCHEMBL3846740 | 0.62 | — | — | |
| SCHEMBL19513420 | 0.62 | KDM4E (0.49) | PLAUPKMLIG1 | |
| SCHEMBL10470577 | 0.59 | HSD17B1 (0.46) | PLAUPKMLIG1 | |
| SCHEMBL19364753 | 0.59 | RAB9A (0.39) | PLAUPKMLIG1 | |
| SCHEMBL4283377 | 0.59 | PKM (0.79) | PLAUPKMLIG1 | |
| SCHEMBL9845734 | 0.59 | HPGD (0.30) | — | |
| SCHEMBL3842026 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421365-A2 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |