Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846131 | 0.92 | MAPT (0.44) | TP53MAPTNPC1RAB9ALMNA | |
| SCHEMBL9846076 | 0.92 | MAPT (0.44) | TP53MAPTNPC1RAB9ALMNA | |
| SCHEMBL9846311 | 0.88 | MAPT (0.44) | TP53MAPTNPC1RAB9ALMNA | |
| SCHEMBL9846108 | 0.82 | MAPT (0.41) | TP53MAPTNPC1RAB9ALMNA | |
| SCHEMBL9449331 | 0.71 | MAPT (0.44) | TP53MAPTNPC1RAB9ALMNA | |
| SCHEMBL9846186 | 0.69 | MAPT (0.48) | TP53MAPTNPC1RAB9ALMNA | |
| SCHEMBL9449235 | 0.67 | ATP4A (0.40) | NPC1RAB9A | |
| SCHEMBL9449238 | 0.67 | ATP4A (0.40) | NPC1RAB9A | |
| 2-Phenethylbenzo[D]Oxazole SCHEMBL10582102 | 0.67 | MAPT (0.81) | TP53MAPTNPC1RAB9ALMNA | |
| SCHEMBL9680846 | 0.67 | L3MBTL1 (0.40) | TP53MAPTNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |