Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.36 |
| ▸ | KDM6B | O15054 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | AOC1 | P19801 | 3/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846137 | 0.77 | CYP2E1 (0.34) | AOC1AOC3CA12CA1CA2 | |
| SCHEMBL9846210 | 0.76 | GALR3 (0.36) | KDM4CKDM6BTRPV1 | |
| SCHEMBL21782174 | 0.72 | AOC1 (0.56) | KDM4CKDM6BPTGS1PTGS2AOC1 | |
| SCHEMBL9846115 | 0.72 | KDM4C (0.35) | KDM4CKDM6BLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL11478702 | 0.71 | KDM4C (0.52) | KDM4CKDM6BPTGS1LMNAL3MBTL1 | |
| SCHEMBL23792402 | 0.70 | AOC1 (0.57) | KDM4CKDM6BPTGS1PTGS2AOC1 | |
| SCHEMBL11628002 | 0.67 | AOC1 (0.53) | KDM4CKDM6BPTGS1PTGS2AOC1 | |
| SCHEMBL15229807 | 0.65 | MAPT (0.45) | LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9846279 | 0.65 | GPBAR1 (0.36) | — | |
| SCHEMBL9846099 | 0.64 | KCNH2 (0.38) | KDM4CKDM6BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424538-A1 | PYRIDINE DERIVATIVES AND THEIR SALTS, AND INSECTICIDAL/ACARICIDAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-05-02 | — | — | EP | disclosed |