SCHEMBL9846279

SCHEMBL9846279

CCc1cnccc1N(C)C(=O)CC(C)CC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 9/20 0.36
RIPK1 Q13546 1/20 0.32
MLYCD O95822 1/20 0.31
TACR1 P25103 2/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9846210 0.73 GALR3 (0.36)
SCHEMBL9846115 0.69 KDM4C (0.35)
SCHEMBL9846137 0.69 CYP2E1 (0.34)
SCHEMBL10843139 0.68 SLC6A2 (0.41) SLC6A2SLC6A4
SCHEMBL31415245 0.68 SLC6A2 (0.41) SLC6A2SLC6A4
SCHEMBL11224374 0.66 CHRNB2 (0.35)
SCHEMBL9846363 0.65 KDM4C (0.36)
SCHEMBL5857902 0.64 CTDSP1 (0.40)
SCHEMBL9846099 0.64 KCNH2 (0.38)
SCHEMBL11388865 0.63 LMNA (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424538-A1 PYRIDINE DERIVATIVES AND THEIR SALTS, AND INSECTICIDAL/ACARICIDAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-05-02 EP disclosed