Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 4/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | AOC1 | P19801 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27335859 | 0.80 | AOC1 (0.41) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6 | |
| SCHEMBL9846363 | 0.77 | KDM4C (0.36) | AOC1AOC3CA12CA1CA2 | |
| SCHEMBL9586338 | 0.77 | LMNA (0.39) | CYP2D6CYP2A6CYP3A4LMNA | |
| SCHEMBL9846115 | 0.76 | KDM4C (0.35) | LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL13844563 | 0.73 | CYP2E1 (0.41) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6 | |
| SCHEMBL9846259 | 0.73 | CYP2E1 (0.36) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6 | |
| SCHEMBL9586839 | 0.73 | RIPK1 (0.40) | LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8271491 | 0.73 | CYP2E1 (0.49) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6 | |
| SCHEMBL877689 | 0.72 | CYP2E1 (0.48) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6 | |
| SCHEMBL9846235 | 0.71 | CYP2E1 (0.35) | CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424538-A1 | PYRIDINE DERIVATIVES AND THEIR SALTS, AND INSECTICIDAL/ACARICIDAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-05-02 | — | — | EP | disclosed |