SCHEMBL9846210

SCHEMBL9846210

CCc1cnccc1NC(=O)CC(C)CC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GALR3 O60755 1/20 0.36
NR2F2 P24468 1/20 0.36
TRPV1 Q8NER1 1/20 0.35
NOD2 Q9HC29 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KDM6B O15054 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
FPR1 P21462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9846099 0.86 KCNH2 (0.38) NOD2KDM4EALDH1A1HSD17B10KDM6B
SCHEMBL9846363 0.76 KDM4C (0.36) TRPV1KDM6BKDM4C
SCHEMBL9846279 0.73 GPBAR1 (0.36)
SCHEMBL20732520 0.73 TSHR (0.44) ALDH1A1KDM6BKDM4CFPR1
SCHEMBL23674773 0.71 CYP17A1 (0.48)
SCHEMBL9846115 0.70 KDM4C (0.35) TRPV1KDM4EALDH1A1KDM6BKDM4C
SCHEMBL9846137 0.70 CYP2E1 (0.34)
SCHEMBL6230352 0.69 LMNA (0.41) KDM4EALDH1A1HSD17B10
SCHEMBL19116577 0.68 SMN1; SMN2 (0.47) KDM4EALDH1A1HSD17B10KDM6BKDM4C
SCHEMBL23792402 0.68 AOC1 (0.57) KDM6BKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424538-A1 PYRIDINE DERIVATIVES AND THEIR SALTS, AND INSECTICIDAL/ACARICIDAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-05-02 EP disclosed