Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846679 | 0.81 | SIGMAR1 (0.33) | PIK3CD | |
| SCHEMBL8129019 | 0.72 | KMT2A (0.37) | MEN1KMT2AALDH1A1KDM4EPIK3CD | |
| SCHEMBL9846720 | 0.72 | PBRM1 (0.37) | LMNA | |
| SCHEMBL9846798 | 0.69 | PDE4A (0.39) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL9372884 | 0.69 | CASP6 (0.39) | MEN1KMT2AALDH1A1KDM4ECHRNB4 | |
| SCHEMBL9372313 | 0.68 | CASP6 (0.39) | MEN1KMT2AALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL3023244 | 0.66 | HSD17B10 (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29634204 | 0.65 | CYP3A4 (0.48) | ACHENR3C1PGRARMEN1 | |
| SCHEMBL28520051 | 0.65 | CYP3A4 (0.48) | ACHENR3C1PGRARMEN1 | |
| SCHEMBL9144338 | 0.62 | ALDH1A1 (0.44) | ACHENR3C1PGRARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |